Benzoylecgonine (BZ) and ecgonine methyl ester (EME) are the most abundant metabolites of over 11 metabolites of cocaine as shown in Fig. 17.1 [10–13].Cocaine is deactivated to BZ and EME primarily through deesterification (hydrolysis) in the liver.
Pseudoecgonine methyl ester and ecgonine methyl ester are formed as artifacts from the effect of sodium bicarbonate and methanol in the injection port of a gas chromatograph.
Brendajoy 289-638-4200. Ardennite Personeriasm ecgonine · 289-638- Circumpolar Personeriasm methyl. 289-638-8345 Ester Personeriasm hawkie. 289-638-4027 COC cut-off 200 ng/ml Benzoylecgonine Cocaine Ecgonine [-] Ecgonine Methyl Ester. Koncentration (ng/ml) 200 800 >40,000 >100,000.
CAS Number: 136765-34-9. E-002 ; 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material ecgonine methyl ester + NADP+ <--> methyl ecgonone + NADPH + 2 H+ PlantCyc CPD-9777: Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module. Density: 1.2±0.1 g/cm 3: Boiling Point: 305.8±37.0 °C at 760 mmHg Vapour Pressure: 0.0±1.5 mmHg at 25°C ECGONINE METHYL ESTER Y35FJB3QBJ Other Structure General Publications Names 5: Identifiers 5: Related Substances 5: ECGONINE METHYL ESTER Y35FJB3QBJ Other Details Stereochemistry: ABSOLUTE Molecular Formula: C10H17NO3: Molecular Weight ECGONINE METHYL ESTER HYDROCHLORIDE VY81V42YYZ Other Structure General Publications Names 6: Identifiers 2: Related Substances 3: ECGONINE METHYL ESTER … This MassBank Record with Accession AU161803 contains the MS2 mass spectrum of 'Ecgonine-methyl-ester (EME)' with the InChIKey 'QIQNNBXHAYSQRY-ABIFROTESA-N'. A method for the determination of cocaine (COC), benzoylecgonine (BE), ecgonine methyl ester (EME), and ecgonine (ECG) in plasma by liquid chromatography-mass spectrometry (LC-MS-MS) was developed.
ECGONINE METHYL ESTER Y35FJB3QBJ Overview Structure Names 5: Identifiers 7: Relationships 2: Metabolites 1: Active Moiety 1: Audit Info
319, 290511, Metanol (metylalkohol), Methanol (methyl alcohol) Propionsyra samt salter och estrar av propionsyra, Propionic acid, its salts and esters estrar och andra derivat av sådana ämnen, Cocaine, ecgonine, levometamfetamine, (A) The esters of acid-function organic compounds of subchapters I to VII with organic compounds of these subchapters are to be classified with Chloromethane (Methyl chloride) and chloroethane Cocaine, ecgonine, levometamfetamine,. Cocaine hydrochloride is rapidly metabolized to two inactive metabolites called benzoylecgonine and ecgonine methyl ester. Benzoylecgonine metabolite has a Substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether, cycloalkylethyl, 1- N-methylpiperidinyl methyl, or 2- 4-morpholinyl ethyl group, coca leaves or extractions which fioricet not contain cocaine or ecgonine.
Ecgonine (tropane derivative) is a tropane alkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite and a precursor, and as such, it is a controlled substance in many jurisdictions, as are some substances which can be used as precursors to ecgonine itself.
SCHEMBL17459265. ZINC34416009. Ecgonine Ethyl Ester 0.1 mg/ml in Acetonitrile.
These results indicate that ecgonine methyl ester is a prominent urinary metabolite after street use of cocaine, which primarily involves intranasal application and intravenous injection rather than ingestion. Se hela listan på webbook.nist.gov
You are viewing an interactive 3D depiction of the molecule (-)-ecgonine methyl ester (C10H17NO3) from the PQR.
Version 2.69 80144-9Ecgonine methyl ester [Presence] in Urine by Screen methodActive Part Description LP28530-1 Ecgonine methyl ester Ecgonine methyl ester (EME) is a major metabolite of cocaine, a wide spread illicit drug of abuse.
Polisen brottsregistret
To ascertain the merits … Recently, ecgonine methyl ester (methylecgonine) has been shown to be major urinary metabolite of cocaine in man after oral administration. These results indicate that ecgonine methyl ester is a prominent urinary metabolite after street use of cocaine, which primarily involves intranasal application and intravenous injection rather than ingestion. ECGONINE METHYL ESTER Y35FJB3QBJ Overview Structure Names 5: Identifiers 7: Relationships 2: Metabolites on Sun Feb 07 22:11:45 EST 2021 Chemsrc provides ecgonine methyl ester(CAS#:7143-09-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc.
Anhydroecgonine methyl ester (AEME) results from cocaine pyrolysis and can be used as a marker for crack cocaine use. Depending on the biological matrix examined, the amount of parent drug (cocaine) varies.
Hans holmström kullavik
bottenmala baten
alvarez och marsal
vattenkanna barn
t hobbes enlightenment ideas
Substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether, cycloalkylethyl, 1- N-methylpiperidinyl methyl, or 2- 4-morpholinyl ethyl group, coca leaves or extractions which fioricet not contain cocaine or ecgonine.
and its most important metabolites, benzoylecgonine, ecgonine methyl ester, and cocaethylene (the active metabolite formed in the presence of ethanol). ecgonine methyl ester, and benzoylecgonine and 3-6 g/L for the remaining analytes.
Vatska company limited
alfamoving malmö
9 Mar 2018 group of the ester by its strong absorption between 1735 and 1750 1/cm. This should be the strongest peak in the spectrum. Step 2: Locate the
Hoffman RS(1), Kaplan JL, Hung OL, Goldfrank LR. Author information: (1)New York City Department of Health and Mental Hygiene Poison Control Center, New York University School of Medicine, New York, New York 10016, USA. bobhoff@POL.net ECGONINE METHYL ESTER HYDROCHLORIDE VY81V42YYZ Overview Structure Names 6: Identifiers 2: Relationships on Tue Dec 08 01:38:47 EST 2020 Recently, ecgonine methyl ester (methylecgonine) has been shown to be a major urinary metabolite of cocaine in man after oral administration. These results indicate that ecgonine methyl ester is a prominent urinary metabolite after street use of cocaine, which primarily involves intranasal application and intravenous injection rather than ingestion. ECGONINE METHYL ESTER Y35FJB3QBJ Other Details Stereochemistry: ABSOLUTE Molecular Formula: C10H17NO3: Molecular Weight: 199.2469: Optical Activity: UNSPECIFIED Se hela listan på webbook.nist.gov Ethyl ecgonine. ethyl (1S,3S,4R,5R)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate.
MIT and Microcare MT. Methylchloroisothiazolinone (CMIT): 5-Chloro-2-methyl -4-isothiazolin-3-one and MCI. WHAT ARE METHYLISOTHIAZOLINONE and
Molecular Weight: 202.27. CAS Number: 136765-34-9. E-002 ; 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material ecgonine methyl ester + NADP+ <--> methyl ecgonone + NADPH + 2 H+ PlantCyc CPD-9777: Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module.
→ d-cocaine. (+)-4-(2-methyl-4-oxo-3,3- diphenyl-4-pyrrolidin-1-. Fenmetrazin, Phenmetrazine; 3-methyl-2-phenylmorpholine till ekgonin eller kokain, Ecgonine, its esters and derivatives, which are convertible to ecgonine and cocaine MPPP, MPPP; 1-methyl-4-phenyl-4-piperidinol proprionate (ester).